melanotic meningioma

Intracranial
melanocytic meningeal tumours and melanosis oculi: case report and literature review. Brain MRI. A) Unenhanced turbo-spin-echo T1-weighted sagittal image documenting the space occupying lesion at the level of the left frontal convexity (white arrow).B) Contrast-enhanced fat-suppressed turbo-spin-echo T1-weighted axial image. MRI documenting the space occupying lesions at the level of the right petrous apex (white arrow) and left cavernous sinus (black arrow).
bmccancer.biomedcentral.com • CC-by-2.0
Intracranial
melanocytic meningeal tumours and melanosis oculi: case report and literature review. Neuroradiological findings at diagnosis of the lesion inside the cavernous sinus. Contrast enhanced CT (A), documenting the space occupying lesion in the left cavernous sinus. T1-weighted images documenting the lesion, which is spontaneously hyper-intense (sagittal view; B – white arrow) and has scarce contrast-enhancement (fat suppressed turbo spin echo T1-weighted axial images after contrast enhancement; C). Axial source image from MR-angio ruled out a vascular lesion (D). The mass lesion remained hyper-intense on un-enhanced fat-saturation T1-weighted images (E), strongly hypo-intense on turbo-spin echo fat-saturated T2-weighted images (F), and iso-intense on gradient echo T2*-weighted images (G).
bmccancer.biomedcentral.com • CC-by-2.0
Spinal
meningeal melanocytoma in a 5-year-old child: a case report and review of literature. a Preoperative MRI T1WI with contrast. b Intraoperative view with the lesion under the nerve roots. c During tumor removal. d Postoperative MRI T1WI with contrast
ejnpn.springeropen.com • CC-by-4.0
Primary
meningeal melanocytoma of the anterior cranial fossa: a case report and review of the literature. Preoperative MR images showing the left frontal tumor with lobulation, ventricle compression and midline shift. A: Axial view. The lesion appears hyperintense on T1-weighted images. B: Axial view. Hypointense signals are noted on T2-weighted image of the brain. C: Axial post contrast T1-weighted view. Contrast enhancement of the tumor. D: Sagittal view. Adhesion of the tumor to the meninges of the anterior cranial fossa (arrow) MR, magnetic resonance.
wjso.biomedcentral.com • CC-by-2.0
Primary
meningeal melanocytoma of the anterior cranial fossa: a case report and review of the literature. CTA of the brain showing the association of the tumor with adjacent vascular structures. A: Axial computed tomography angiography (CTA). The tumor compressed the ipsilateral anterior and middle cerebral artery (arrows). B-C: CTA image. The tumor was fed by branching arteries from the middle and anterior cerebral arteries.
wjso.biomedcentral.com • CC-by-2.0
Intracranial
meningeal melanocytoma diagnosed using an interdisciplinary approach: a case report and review of the literature. Magnetic resonance imaging demonstrating a tumor 10 mm in diameter. a T1-weighted axial images (repetition time 667/echo time 9) revealed a homogeneously high signal tumor in Meckel’s cave. b T2-weighted axial images (repetition time 5200/echo time 98) revealed a low signal tumor exerting pressure on trigeminal nerve
jmedicalcasereports.biomedcentral.com • CC-by-4.0
Intracranial
meningeal melanocytoma diagnosed using an interdisciplinary approach: a case report and review of the literature. Unenhanced computed tomography image at referral hospital. A localized well-defined mass in Meckel’s cave, homogeneously hyperdense to the gray matter
jmedicalcasereports.biomedcentral.com • CC-by-4.0
Primary
melanocytic tumors of the CNS • Primary intramedullary melanocytoma - thoracic spine - Ganzer Fall bei Radiopaedia
Boscà, A. Primary intramedullary melanocytoma - thoracic spine. Case study, Radiopaedia.org. (accessed on 21 Oct 2022) https://doi.org/10.53347/rID-58570 • CC by-nc-sa 3.0 (modified)
Radiopaedia • CC-by-nc-sa 3.0 • de

Melanotic meningioma is a rare histological variant of WHO grade I (benign) meningioma.

Epidemiology

As only several dozen cases have been reported in the literature, no significant difference in prevalence has been found between genders/age groups.

Pathology

Melanotic meningiomas arise from leptomeningeal melanocytes, small pigment cells found mostly in the meninges covering the ventrolateral surfaces of the medulla oblongata, posterior cranial fossa or Meckel cave .

Radiographic features

Given the small number of reported cases it is difficult to determine the most characteristic appearance.

CT

These tumors are most commonly isodense to grey matter, with variable enhancement .

MRI

Different signal intensities are probably correlated with the amount of melanin in the pigment cells. Possible causes of low signal intensity on T2-weighted sequences include decreased water content, paramagnetism, susceptibility effects or hemorrhage .

  • T1: iso- or hyperintense
  • T2: hypo- or hyperintense
  • T1 C+: homogenous enhancement

Treatment and prognosis

Similar to other meningiomas the treatment of melanotic meningiomas is usually surgical excision, with complete tumor removal being the best therapeutic option (in terms of disease-free survival) .

Siehe auch:
und weiter:
Assoziationen und Differentialdiagnosen zu meningeales Melanozytom:
Ependymom
 
Wikipedia • CC BY-SA 3.0
Astrozytom
 
Wikipedia • CC BY-SA 3.0
Hämangioblastom
 
Wikipedia • CC BY 2.5
Kavernom
 
Wikipedia • CC BY-SA 4.0
meningeale
Tumoren
Wikipedia • CC BY-SA 4.0