primäres Lymphom der Pleura

Primary pleural lymphoma is extremely rare, especially in immunocompetent patients.

Epidemiology

Primary pleural lymphoma accounts for <0.5% of all non-Hodgkin lymphoma  and ~2.5% of primary chest wall tumors .

Pathology

Primary pleural lymphoma may be Hodgkin or non-Hodgkin lymphoma with diffuse large B-cell accounting for the majority (60%) of cases .

Etiology

Primary pleural lymphoma has been described in the setting of chronic inflammation or in immunocompromised patients :

  • body-cavity (i.e. pleural, pericardial or peritoneal) based in patients with HIV
  • associated with tuberculosis pyothorax

Case reports exist of primary pleural lymphoma in immunocompetent patients with other proposed causative factors :

Radiographic features

Primary pleural lymphoma may presents with non-specific features :

Differential diagnosis

Other types of pleural tumors should be considered.

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