carcinoid
Kleiner
intraluminaler Tumor des Dünndarms (gelber Pfeil). Assoziierter Tumor im Mesenterium mit spikulierter Kontur und desmoplastischer Reaktion bei Karzinoid des Dünndarms.
Carcinoid
tumor • Terminal ileum carcinoid tumor - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Carcinoid tumor - terminal ileum - Ganzer Fall bei Radiopaedia
Carcinoid
syndrome • Carcinoid syndrome - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Mesenteric neuroendocrine tumor deposit with small bowel ischemia - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Carcinoid tumor of the ileum with metastasis to orbit - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Small bowel carcinoid tumor - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Small bowel neuroendocrine tumor with liver metastases - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Carcinoid tumor with liver metastases - Ganzer Fall bei Radiopaedia
Hypervascular
liver lesions • Hepatic carcinoid - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Terminal ileum carcinoid - well differentiated neuroendocrine tumor (pathology) - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Liver metastases from carcinoid - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Carcinoid tumor with hepatic metastases - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Carcinoid tumor - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Carcinoid tumor of jejunum - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Intestinal carcinoid tumor - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Malignant carcinoid of the stomach with metastases - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Pulmonary carcinoid with hepatic metastases - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Small bowel carcinoid tumor - Ganzer Fall bei Radiopaedia
Carcinoid
tumor • Carcinoid tumor - Ganzer Fall bei Radiopaedia
Carcinoid tumors are a type of neuroendocrine tumor that can occur in a number of locations. Carcinoid tumors arise from endocrine amine precursor uptake and decarboxylation (APUD) cells that can be found throughout the gastrointestinal tract as well as other organs (e.g. lung). In general, they are slow-growing tumors but are nevertheless capable of metastasizing.
Clinical presentation
- can be variable, dependent on the location:
- carcinoid tumors involving the jejunum and ileum can be large at presentation but are usually found incidentally
- rectal carcinoids may cause pain
- gastrointestinal tract carcinoid can present as vague abdominal pain
- carcinoid syndrome: in 8% of patients with a carcinoid tumor
Pathology
Location
- gastrointestinal tract carcinoid (60-85% of all carcinoids)
- small bowel: ~40% of gastrointestinal carcinoids, mostly in the terminal ileum
- rectum (~22.5%)
- colon (~15%)
- appendix (~10%)
- stomach (~7.5%)
- pancreas (~7.5%)
- carcinoid tumors of the lung (~25% of all carcinoids)
- primary hepatic carcinoid
- ovarian carcinoid: accounts for 0.5% of carcinoid tumors and 0.3% of ovarian tumors
- thymic carcinoid
Markers
- 5-HIAA (5-hydroxyindoleacetic acid): usually suggests a functioning carcinoid tumor
- chromogranin A (CgA): considered a valuable tool in the diagnosis of neuroendocrine neoplasia in general
Radiographic features
CT/MRI
Refer to specific articles (above) for imaging characteristics.
Nuclear medicine
- gallium-68 octreotide PET/CT (e.g. Ga-68 DOTATATE) has shown improved accuracy for detection of neuroendocrine tumors relative to indium-111 pentetreotide (Octreoscan) SPECT/CT
- indium-111 octreotide (e.g. Octreoscan) SPECT/CT
- iodine-123 MIBG will also concentrate on carcinoid tumors, including the low percentage (~15%) that are negative with indium-111 octreotide
Treatment and prognosis
Complications
History and etymology
It was initially coined by Oberndorfer in 1907 as “karzinoide” to denote its resemblance to carcinoma .
Siehe auch:
- Dünndarmkarzinoid
- Somatostatin-Rezeptor-Szintigrafie
- Karzinoidsyndrom
- pulmonary carcinoid tumours
- midgut carcinoid tumor
- carcinoid tumour in Meckel's diverticulum
- Karzinoid des Thymus
- peripheral pulmonary carcinoid tumours
- bronchiales Karzinoid
- cardiac valve lesions from carcinoid
- ovarian carcinoid
- Karzinoid der Appendix
und weiter:
- hypervaskularisierte Leberläsionen
- osteoblastische Knochenmetastasen
- mesenteriale Pannikulitis
- Neurofibromatose Typ 1
- Ileitis terminalis
- solitärer pulmonaler Rundherd
- Dünndarmtumoren
- MIBG
- hyperdenser Lymphknoten
- duodenal filling defects
- ultrasound appearances of liver metastases
- multiple endokrine Neoplasie Typ 1
- Hedinger-Syndrom
- carcinoid tumours of the lung
- fat ring sign
- ovarian carcinoid tumours
- peripheral pulmonary carcinoid tumour
- thymic carcinoid tumour
- fat halo sign of mesenteric panniculitis
- Knochenmetastasen bei Karzinoid
- carcinoid of the terminal ileum
- primary renal carcinoid tumor
- sclerosing mesentritis
- Cup Syndrom
- metastatic carcinoid tumor
- hypervaskularisierte Lymphknoten
- primary hepatic carcinoid
- Rektumkarzinom
- abdominelle und pelvine Verkalkungen
- endobronchial carcinoid tumor
- spikulierte Periostreaktion
- Karzinoid des Duodenums
- hyperdense pulmonale Raumforderungen
Assoziationen und Differentialdiagnosen zu Karzinoid: