chondrosarcoma grading

Chondrosarcoma grading allows the division of chondrosarcoma into 3 (sometimes 4) grades.

Grade 1 - low grade

• low cellularity
• mostly chondroid matrix
• little if any myxoid
• difficult to distinguish from enchondroma (see enchondroma vs. low grade chondrosarcoma for imaging distinguishing features)

• e.g.
  • conventional chondrosarcoma
  • juxtacortical chondrosarcoma

Grade 2 - intermediate grade

• increased cellularity
• little chondroid matrix
• necrosis and more common prominent myxoid

• e.g
  • conventional chondrosarcoma
  • juxtacortical chondrosarcoma
  • myxoid chondrosarcoma

Grade 3 - high grade

• highly cellular
• nuclear pleomorphism
• absent chondroid matrix
• stroma present is myxoid

• e.g.
  • conventional chondrosarcoma
  • juxtacortical chondrosarcoma
  • mesenchymal chondrosarcoma
  • dedifferentiated chondrosarcoma

Siehe auch:

• Enchondrom
• Chondrosarkom
• Unterscheidung Enchondrom Chondrosarkom
• juxtakortikales Chondrosarkom
• dedifferentiated chondrosarcoma
• conventional chondrosarcoma

und weiter:

• conventional intramedullary chondrosarcoma
• myxoid chondrosarcoma