renal osteodystrophy

Renal osteodystrophy (ROD), also known as uremic osteopathy, is a constellation of musculoskeletal abnormalities that occur in patients with chronic renal failure, due to concurrent and superimposed:

  • osteomalacia (adults)/rickets (children)
  • secondary hyperparathyroidism: abnormal calcium and phosphate metabolism
    • bone resorption
    • osteosclerosis
    • soft tissue and vascular calcifications
    • brown tumors
  • aluminum intoxication, e.g. if the patient is on dialysis

Radiographic features

Imaging findings are many and varied:

Differential diagnosis

General imaging differential considerations include